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Evidence of link between exposure to aluminium and MS

Submitted by an LD OnLine user on

http://www.news-medical.net/?id=15956

[NOTE: Aluminum has be tied toalzheimer’s and other
neurological disorders, and is only incrimentally less
toxic that mercury and lead, espcially in certain organic
forms.]

Scientists at Keele University in Staffordshire have
discovered the first evidence of a link between human
exposure to aluminium and multiple sclerosis.
Their research has demonstrated very high (up to 40 times
the control level) urinary excretion of aluminium in MS,
particularly so in the relapsing-remitting form of the
disease. Urinary excretion of iron was also significantly
elevated in MS and particularly so in the secondary
progressive form of the disease.

Urinary excretion of silicon, the ‘natural’ antagonist to
the potential toxicity of aluminium, was decreased in MS
and particularly so in secondary progressive form of the
disease.

The research suggests that individuals with MS have a
higher body burden of aluminium and that their urinary
excretion of aluminium is linked to changes taking place
during the relapsing-remitting stage of the disease.

Dr Christopher Exley, Birchall Centre for Inorganic
Chemistry and Materials Science, Lennard-Jones
Laboratories, Keele University, Staffordshire, said: “If,
as is currently believed, MS is a disorder resulting from
the interplay between the environment and susceptibility
genes then our observation of elevated excretion of iron
may be indicative of the latter, while elevated excretion
of aluminium suggests that exposure to aluminium may be the
hitherto unrecognised environmental factor in MS.”

Other researchers involved in the study were: Godwin
Mamutse, Olga Korchazhkina, Eleanor Pye, Stanislav
Strekopytov, Anthony Polwart, Clive Hawkins.

http://www.keele.ac.uk

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