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Plasma Amino Acid Levels In Children With Autism

Submitted by an LD OnLine user on

Yet another small piece of the puzzle which demonstrates that the anecdotal reports of leaky gut syndrome are valid.

Plasma Amino Acid Levels In Children With Autism And Their Families.

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12708584&dopt=Abstract < - - address ends here.
Aldred S, Moore KM, Fitzgerald M, Waring RH.
Pharmaceutical Sciences Research Institute, Aston University, Birmingham, B4
7ET, United Kingdom.

Plasma amino acid levels were measured in autistic and Asperger syndrome patients, their siblings, and parents. The results were compared with values from age-matched controls. Patients with autism or Asperger syndrome and their siblings and parents all had raised glutamic acid, phenylalanine, asparagine, tyrosine, alanine, and lysine (p < .05) than controls, with reduced plasma glutamine. Other amino acids were at normal levels. These results show that children with autistic spectrum disorders come from a family background of dysregulated amino acid metabolism and provide further evidence for an underlying biochemical basis for thecondition.

PMID: 12708584 [PubMed - in process]

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